Search results - 91 results
Detection of tetracycline-resistant and susceptible pasteurellaceae in the nasopharynx of loose group-housed calves.
multocida (57.4%), Mannheimia varigena (4.9%) and M. haemolytica (3.2%). Growth of Pasteurellaceae on the OTC-containing medium was seen only with samples from two herds (6 animals; 9.8%), and on only one ...
In vitro activities of ceftobiprole, tigecycline, daptomycin, and 19 other antimicrobials against methicillin-resistant Staphylococcus aureus strains from a national survey of Belgian hospitals
Publication Type: Peer reviewed scientific article Authors: O. Denis; Deplano,A.; Nonhoff,C.; Hallin,M.; De Ryck,R.; R. Vanhoof; de Mendonca,R.; M. Struelens Source: Antimicrob.Agents Chemother., ...
Molecular characterization of genes associated with ethionamide resistance in Mycobacterium tuberculosis clinical isolates and spontaneous mutants
Publication Type: Scientific poster, presentation or proceeding Authors: Vanessa Mathys; Baulard,A.; Kurepina,N.; M. Fauville; B.N. Kreiswirth; Bifani,P. Source: 106th General Meeting, NA, Issue ...
Immunogenicity and protective efficacy of tuberculosis DNA vaccines combining mycolyl-transferase Ag85A and phosphate transport receptor PstS-3.
vector and Ag85A specific levels being lower in mice vaccinated with the combination pBudCE4.1 vector (as compared to levels obtained following single plasmid immunization). Protection against M. ...
Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.
PstS-3, known to encode a dominant D(b)-restricted CD8 +-T-cell epitope, displayed CD8 +-T-cell responses not observed in CD4-/- mice. M. tuberculosis challenge in reconstituted mice led to the ...
Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv.
Mice were monitored for cachexia and survival following a low dose intravenous challenge with M. tuberculosis H37R v. Priming with Ag85A but not control DNA increased significantly the protective ...
Mycobacterium tuberculosis with disruption in genes encoding the phosphate binding proteins PstS1 and PstS2 is deficient in phosphate uptake and demonstrates reduced in vivo virulence.
inactivated, we showed that these pstS genes encode high-affinity phosphate binding proteins. In a mouse infection model, both mutants were attenuated in virulence, suggesting that M. tuberculosis encounters ...
National surveillance of methicillin-resistant Staphylococcus aureus in Belgian hospitals indicates rapid diversification of epidemic clones
Publication Type: Peer reviewed scientific article Authors: O. Denis; Deplano,A.; Nonhoff,C.; De Ryck,R.; de Mendonca,R.; Rottiers,S.; R. Vanhoof; M. Struelens Source: Antimicrob.Agents Chemother., ...
Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.
peptide-pulsed syngeneic spleen cells from naive animals into DNA vaccinated or M. tuberculosis-infected recipients, we demonstrated a functional in vivo CTL activity against this D(b)-restricted PstS-3 epitope. ...
Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.
antigen presenting cells. MHC class I bound peptides were acid eluted from the surface of RMA-S cells incubated with M. tuberculosis culture filtrate proteins. The crude peptide preparation was able to ...