Search results - 57 results
Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays.
Demaegdt; Mertens, Birgit; Karine Vandermeiren; Scippo, Marie-Louise; Elskens, Marc Source: Toxicol In Vitro, Volume 37, p.121-133 (2016) Keywords: Animals Biological Assay Bottle Feeding Cell Line Cell Line, ...
Pseudorabies virus isolates from domestic pigs and wild boars show no apparent in vitro differences in replication kinetics and sensitivity to interferon-induced antiviral status.
Animals Antiviral Agents Cells, Cultured Herpesvirus 1, Suid Interferons Sus scrofa Viral Plaque Assay Virus Replication Abstract: Pseudorabies virus is the causative agent of Aujeszky’s disease. Domestic ...
Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test.
concentration, catalytic and biological activities. For BoNT/A₁, B₁ and E₁, serotypes pathogenic to humans, the catalytic activity and the precise protein concentration were determined by Endopep-mass spectrometry ...
Systematic identification of hypothetical bacteriophage proteins targeting key protein complexes of pseudomonas aeruginosa
assays, we further mapped the inhibitory interaction of gp12 of phage 14-1 to the alpha subunit of the RNA polymerase. Together, our data demonstrate the powerful use of interactomics to unravel the ...
2,4-Dialkyl-8,9,10,11-tetrahydrobenzo[g]pyrimido[4,5-c]isoquinoline-1,3,7,12(2H,4H)-tetraones as new leads against Mycobacterium tuberculosis.
dialkyltetrahydrobenzo[g]pyrimido [4,5-c]isoquinolinetetraones were designed and synthesised. The compounds were submitted to a biological evaluation in which the activity against M.tb H37R v(lux) was observed, as well as the acute ...
Laboratory diagnosis of paediatric tuberculosis in the European Union/European Economic Area: analysis of routine laboratory data, 2007 to 201136508
VALIDATION values Abstract: Laboratory confirmation of paediatric tuberculosis (TB) is frequently lacking. We reviewed the range of routine laboratory tests and their performance in different biological ...
Biological evaluation of diazene derivatives as anti-tubercular compounds.
Huygen, Kris; Košmrlj, Janez Source: Eur J Med Chem, Volume 74, p.85-94 (2014) Keywords: Antitubercular Agents Drug Screening Assays, Antitumor Imides Abstract: Despite efforts made in chemotherapeutic ...
Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect.
adipogenesis model, and direct fluorescent measurement using Nile red lipid staining technique. In a first phase, we characterised the assay using the acknowledged obesogens rosiglitazone and tributyltin. Based ...
Biological evaluation of bisbenzaldehydes against four Mycobacterium species.
an intracellular growth inhibition assay of M. tb in murine J774 A.1 macrophages. None of the compounds showed significant cytotoxicity on human C3A hepatocytes in a neutral red dye uptake assay and no ...
Angiotensin IV displays only low affinity for native insulin-regulated aminopeptidase (IRAP).
Radioligand Assay Tyrosine Zinc Abstract: Radioligand binding studies revealed that Ang IV binds to insulin-regulated aminopeptidase (IRAP)/' AT (4) receptors' with high affinity. Yet, as these ...