Search results - 41 results
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Birgit Mertens Source: 57th Congress of the European Societies of Toxicology, Ljubljana, Slovenia (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment ...
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Birgit Mertens Source: Joint 3R Symposium, Brussels, Belgium (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment (IATA) pollutants Health Topics: ...
Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment
Publication Type: Scientific poster, presentation or proceeding Authors: Alexandra Schaffert; Sivakumar Murugadoss; Birgit Mertens; Tom Roos; Ronette Gehring; Nunzia Linzalone; Gabriele Donzelli; ...
A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance
Publication Type: Scientific poster, presentation or proceeding Authors: T. Roos; C. Leenaars; A. Schaffert; M. Paparella; S. Murugadoss; Birgit Mertens; N. Linzalone; G. Donzelli; M. ...
Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.
Publication Type: Peer reviewed scientific article Authors: Alexandra Schaffert; Sivakumar Murugadoss *; Birgit Mertens *; Martin Paparella Source: Volume 40, Issue 2 (2023) Keywords: Cardiotoxicity ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
Publication Type: Peer reviewed scientific article Authors: Thienpont, Anouck; Verhulst, Stefaan; Van Grunsven, Leo A; Rogiers, Vera; Vanhaecke, Tamara; Birgit Mertens * Source: ALTEX, Volume 40, ...
Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.
Publication Type: Peer reviewed scientific article Authors: Schaffert, Alexandra; Murugadoss, Sivakumar; Mertens, Birgit; Paparella, Martin Source: ALTEX, Volume 40, Issue 2 (2023) Keywords: ...
Mixtures of genotoxicants: does the principle of additivity apply?
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Sanders; Roel Anthonissen; George Johnson; Tamara Vanhaecke; Birgit Mertens Source: EEMGS meeting, Malaga, Spain (2023) ...
The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...