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The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Chezal, Jean-Michel; Froeyen, Matheus; Leyssen, Pieter; Dutartre, Hélène; Vrancken, Robert; Canard, Bruno; Letellier, ...
Genomic analysis of Pseudomonas aeruginosa phages LKD16 and LKA1: establishment of the phiKMV subgroup within the T7 supergroup.
Publication Type: Peer reviewed scientific article Authors: Pieter-Jan Ceyssens; Lavigne, Rob; Wesley Mattheus; Chibeu, Andrew; Hertveldt, Kirsten; Jan Mast; Robben, Johan; Volckaert, Guido Source: ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Leyssen, Pieter; Mabery, Eric; Boddeker, Nina; Vrancken, Robert; Froeyen, Matheus; Ansari, Israrul H; Dutartre, Hélène; ...
The Magistral Phage.
Publication Type: Peer reviewed scientific article Authors: Pirnay, Jean-Paul; Verbeken, Gilbert; Pieter-Jan Ceyssens; Isabelle Huys; De Vos, Daniel; Charlotte Ameloot; Alan Fauconnier Source: ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
Vanessa Mathys; Pieter-Jan Ceyssens Source: 2nd St. Petersburg Symposium on Tuberculosis and Mycobacteria: Molecular Approach, Issue Institut Pasteur Sint Petersburg, Sint Petersburg (2018) Abstract: ...
Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid
Publication Type: Scientific poster, presentation or proceeding Authors: An Van den Bossche; Hugo Varet; Amandine Sury; Odile Sismeiro; Rachel Legendre; Jean-Yves Coppee; Vanessa Mathys; Pieter ...
The Phage-Encoded-Acetyltransferase Rac Mediates Inactivation of Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
Publication Type: Peer reviewed scientific article Authors: Pieter-Jan Ceyssens; De Smet, Jeroen; Jeroen Wagemans; Natalia Akulenko; Evgeny Klimuk; Subray Hedge; Voet, Marleen; Hendrix, Hanne; ...
Dissecting the molecular evolution of fluoroquinolone-resistant Shigella sonnei.
Niall; Martin Cormican; Sonam Wangchuk; Bodhidatta, Ladaporn; Carl J Mason; Nguyen, To Nguyen Thi; Ha Thanh, Tuyen; Phat Vinh Voong; Duong, Vu Thuy; Phu Huong Lan Nguyen; Paul Turner; Ryan Wick; Pieter ...
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.
Publication Type: Peer reviewed scientific article Authors: Jane Hawkey; Le Hello, Simon; Benoît Doublet; Sophie A Granier; Rene S Hendriksen; Florian W Fricke; Pieter-Jan Ceyssens; Camille Gomart; ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.
Publication Type: Peer reviewed scientific article Authors: An Van den Bossche; Hugo Varet; Amandine Sury; Odile Sismeiro; Rachel Legendre; Jean-Yves Coppee; Vanessa Mathys; Pieter-Jan Ceyssens ...