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GENOMARK, a promising new approach methodology for genotoxicity testing in the cosmetic industry
International cosmetic congress, Antalya, Turkey (2022) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
genetic toxicology GENOMARK biomarker predictive toxicology human health risk assessment new approach methodologies (NAMs) Abstract: Transcriptomics-based biomarkers are promising new approach methodologies ...
Functional reprogramming of monocytes in patients with acute and convalescent severe COVID-19.
different stages of the disease. In patients with acute severe COVID-19, we identified a specific transcriptomic and epigenomic state in monocytes that can account for their functional refractoriness. The ...
Combining a transcriptomics-based gene expression biomarker with the ToxTracker to evaluate the genotoxic potential of high priority printed paper and board food contact material substances
Source: Beltox meeting (2019) URL: https://beltox.be/beltox-annual-meeting-2019-programme/ Keywords: Biomarkers food contact materials Gene Expression genotoxicity Transcriptomics Abstract: presentation at ...
Preparing cDNA Libraries from Lytic Phage-Infected Cells for Whole Transcriptome Analysis by RNA-Seq.
Publication Type: Peer reviewed scientific article Authors: Blasdel, Bob; Pieter-Jan Ceyssens; Lavigne, Rob Source: Methods Mol Biol, Volume 1681, Issue 1681, Number 1941 (2018) Keywords: Bacteriophage RNA-seq Abstract: Whole genome wide analysis of trans ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
approaches, we have developed an upgraded, innovative, and proprietary gene classifier. This gene classifier is based on transcriptomic changes induced by 12 genotoxic and 12 non-genotoxic reference compounds ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
European Society of Mycobacteriology, ESM, Issue ESM, Sibenik, Craotia (2017) Keywords: antibiotics Mycobacterium tuberculosis Transcriptomics Abstract: Background: With 1.5 million deaths in 2014, the most ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
ESCMID, Vienna, Austria (2017) Keywords: antibiotics Mycobacterium tuberculosis Transcriptomics Abstract: Background: With 1.5 million deaths in 2014, the most recent report of the WHO ranks tuberculosis ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
Transcriptome Workflow Abstract: The assessment of the carcinogenic potential of chemicals with alternative, human-based in vitro systems has become a major goal of toxicogenomics. The central read-out of these ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Alessandra; Milushev, Dimiter; Benfenati, Emilio; Rogiers, Vera; Doktorova, Tatyana Y Source: Mutagenesis, Volume 31, Number 461, p.453-61 (2016) Keywords: Cosmetics In silico Mutagenicity Tests Transcriptomics ...