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Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis.

the pyrazinamidase (pncA) gene of a collection of multidrug-resistant tuberculosis (MDR- TB) clinical isolates and PZA-resistant (PZA (r)) spontaneous mutants. The frequency of acquired resistance to ...

Microbiological and molecular assessment of bacteriophage ISP for the control of Staphylococcus aureus

was proven to be stable in relevant in vivo conditions and subcutaneous as well as nasal and oral ISP administration to rabbits appeared to cause no adverse effects. ISP encodes 215 gene products on its ...

Detection of a geographical and endemic cluster of hyper-invasive meningococcal strains.

meningitidis serogroup B, non-serotypeable, subtype P1.14 (B: NT: P1.14). Most cases were geographically clustered in the northern part of the country. Multilocus Sequence Typing and antigen gene sequencing ...

Trends in production of extended-spectrum beta-lactamases among Enterobacteriaceae of clinical interest: results of a nationwide survey in Belgian hospitals.

production was confirmed by phenotypic and genotypic tests. MIC s of 13 antimicrobial agents were determined by Etest. ESBL-encoding genes were identified by PCR sequencing and the bla(CTX-M) environment was ...

Effect of PstS sub-units or PknD deficiency on the survival of Mycobacterium tuberculosis.

Tuberculosis (Edinb), Volume 90, Issue 6, p.338-45 (2010) Keywords: Animals ATP-Binding Cassette Transporters Bacterial Proteins Blotting, Western Cell Proliferation Gene Expression Regulation, Bacterial mice ...

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice.

Mycobacterium tuberculosis infection. Upon intratracheal infection with M. tuberculosis, LXR s and LXR target genes were induced in CD11 c+ lung and alveolar cells. Furthermore, mice deficient in both LXR ...

Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis.

para-aminosalicylic acid (PAS) resistance by analysis of six genes of the folate metabolic pathway and biosynthesis of thymine nucleotides (thyA, dfrA, folC, folP1, folP2, and thyX) and three N-acetyltransferase genes ...

Surveillance of antibiotic susceptibility patterns among Shigella sonnei strains isolated in Belgium during the 18-year period 1990 to 2007.

Keywords: Anti-Bacterial Agents Belgium Child, Preschool DNA Transposable Elements Drug Resistance, Bacterial Dysentery, Bacillary Gene Transfer, Horizontal Humans Infant Microbial Sensitivity Tests R Factors ...

A bacterial population study of commercialized wastewater inoculants.

Sequence Electrophoresis, Agar Gel Enterobacter cloacae Genes, Plant Household Products Housekeeping Humans Klebsiella pneumoniae Molecular Sequence Data polymerase chain reaction RNA, Ribosomal, 16S Sewage ...

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