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Evaluation of impurities and dissolution profiles of illegal antimicrobial drugs encountered in Belgium
Publication Type: Peer reviewed scientific article Authors: Yaxin Tie; Kevin van Loock; Eric Deconinck; Erwin Adams Source: Drug testing and analysis (2019) Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of me ...
Impact of the revised European Tobacco Product Directive on the quality of e-cigarette refill liquids in Belgium
during (2016) and after (2017-2018) the implementation of the TPD revisions, were analyzed for the presence of nicotine, nicotine-related impurities, volatile organic compounds (VOC s), the additives ...
A simple dilute-and-shoot method for screening and simultaneous quantification of nicotine and alkaloid impurities in electronic cigarette refills (e-liquids) by UHPLC-DAD
Biomedical Analysis, Volume 169, Issue 169, Number 234 (2019) Keywords: accuracy profiles e-cigarettes Nicotine nicotine-impurities UHPLC-DAD Abstract: The electronic cigarette (e-cigarette) has emerged as ...
Falsification of biotechnology drugs: current dangers and/or future disasters?
contaminations and product or process related impurities. Moreover, also unauthorized polypeptides or polypeptides which failed clinical trials or are still subject of clinical or pre-clinical assessments have ...
Chemical characterization of electronic cigarette refills (e-liquids) in Belgium
e-cigarettes GC impurities LC Nicotine Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories Efficacité et sécurité des vaccins, médicaments et ...
Impurity profiling of the most frequently encountered falsified polypeptide drugs on the Belgian market
biotherapeutics were already analysed, looking at a specific aspect of their quality or identity, no systematic studies have been performed regarding the presence of different impurities or possible contaminations. ...
An application of mass spectrometry for quality control of biologicals: Highly sensitive profiling of plasma residuals in human plasma-derived immunoglobulin.
angiotensinogen, antithrombin- III, complement component C8, …). Those results emphasize that MS screening is a relevant first-line test to prevent any undesired concentration of plasma impurities after a plasma ...
Chromatographic impurity fingerprinting of genuine and counterfeit Cialis® as a means to compare the discriminating ability of PDA and MS detection.
Publication Type: Peer reviewed scientific article Authors: Custers, D; Krakowska, B; De Beer, J O; Patricia Courselle; Daszykowski, M; Apers, S; Eric Deconinck Source: Talanta, Volume 146, p.540-8 (2016) Keywords: Chromatography, High Pressure Liquid Cou ...
Detection and risk evaluation of counterfeit medicines based on physico-chemical properties: the fingerprint and chemometrics approach
classify counterfeit medicines. The potential use of chromatographic fingerprinting is investigated in Chapter VII. In this chapter a HPLC- PDA and HPLC- MS method were developed to acquire impurity ...
The Monte Carlo validation framework for the discriminant partial least squares model extended with variable selection methods applied to authenticity studies of Viagra® based on chromatographic impurity profiles.
based on the Monte Carlo approach that is used in the context of authenticity studies based on chromatographic impurity profiles. The performance of the validation approach was applied to evaluate the ...