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M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

pulmonary form of TB, which often results from the reactivation of a latent M. tuberculosis (M.tb)infection. Among the new approaches in TB vaccine development, live attenuated M.tb mutants are a promising ...

Palliative care service use in four European countries: a cross-national retrospective study via representative networks of general practitioners.

patients (≥ 18 years) in their practices and the care they received in the last three months of life using a standardized form. Sudden deaths were excluded. RESULTS: We studied 4,466 deaths. GP s perceived ...

Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect.

Our results showed the adipogenic potential of all tested parabens, several musks and phthalate compounds and bisphenol A (BPA). PPAR γ activation was associated with adipogenesis for parabens, ...

Capturing cooperative interactions with the PSI-MI format.

interaction data by defining new controlled vocabulary terms that allow annotation of different aspects of cooperativity without making structural changes to the underlying XML schema. As a result, we are able ...

The origin of biased sequence depth in sequence-independent nucleic acid amplification and optimization for efficient massive parallel sequencing.

obtain viral sequences. However, these studies showed a biased distribution of the resulting sequence reads over the analyzed genomes. The aim of this study was to elucidate the mechanisms that lead to ...

Validation of a commercially available indirect ELISA using a nucleocapside recombinant protein for detection of Schmallenberg virus antibodies.

Nucleocapsid Proteins Orthobunyavirus Reagent Kits, Diagnostic Recombinant Proteins Reproducibility of Results Roc Curve Sheep Abstract: A newly developed Enzym Like Immuno Sorbant Assay (ELISA) based on the ...

Proteomic characterization of murid herpesvirus 4 extracellular virions.

results extend previous work aimed at determining the composition of gammaherpesvirus virions and provide novel insights for understanding MuHV-4 biology. Health Topics:  Animal health Category:  A1 FOS ...

Trends in genotype frequency resulting from breeding for resistance to classical scrapie in Belgium (2006 ˜ 2011).

Publication Type: Peer reviewed scientific article Authors: Alexandre Dobly; Van der Heyden, Sara; S. Roels Source: J Vet Sci, Volume 14, Issue 1, p.45-51 (2013) Keywords: Animals Belgium Breeding Female Genetic Predisposition to Disease Genetic Variation ...

Seroprevalence and potential risk factors for Brucella spp. infection in traditional cattle, sheep and goats reared in urban, periurban and rural areas of Niger.

transmission of Brucella in this context. RESULTS: 5,192 animals from 681 herds were included in the study. Serum samples and hygroma fluids were collected. A household survey enabled to identify the risk ...

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