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Performance of in silico models for mutagenicity prediction of food contact materials
predict the mutagenic potential of substances that are new to the model (i.e. not included in the training set) is reported. In this context, the generally poor sensitivity for these new substances is ...
World Health Organization estimates of the relative contributions of food to the burden of disease due to selected foodborne hazards: A structured expert elicitation
ability to judge uncertainty accurately and informatively using a series of subject-matter specific ‘seed’ questions whose answers are unknown to the experts at the time they are interviewed. Trained ...
Development and validation of a protocol for optimizing the use of paraffin blocks in molecular epidemiological studies: The example from the HPV-AHEAD study.
processing blocks, all sectioning centers underwent a quality control to guarantee a satisfactory training process. The first and last sections of the FFPE s were used for histopathological assessment. ...
DLL4 expression is a prognostic marker and may predict gemcitabine benefit in resected pancreatic cancer.
gemcitabine therapy was statistically significant (P<0.001). The validating cohort recapitulated the findings of the training cohort. CONCLUSIONS: Low DLL4 abundance in tumour cells may predict the benefit ...
Cost-effectiveness analysis in melanoma detection: A transition model applied to dermoscopy.
cohorts were constituted by melanoma patients diagnosed by dermatologists adequately, or not adequately, trained in dermoscopy. Effectiveness and costs were calculated for each cohort and compared. ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
were initially challenged with thirty compounds, genome-wide gene expression was measured with microarrays, and hazard classifiers were built from this training set. Subsequently, each system was ...
External quality assessment for tuberculosis diagnosis and drug resistance in the European Union: A five year multicentre implementation study
performance prevention problems Pyrazinamide Quality QUALITY ASSURANCE resistance result results SB- IM specific State States study Sweden System Systems Test TESTING training Tuberculosis United Kingdom ...
Belgian hand hygiene campaigns in ICU, 2005-2015.
trained infection control teams measured adherence to HH guidelines by direct observation. HH opportunities were counted and the actual episodes of HH were scored as no HH, HH with water and soap, or HH ...
Short-term health effects in the general population following a major train accident with acrylonitrile in Belgium.
Abstract: BACKGROUND: Following a train derailment, several tons of acrylonitrile (ACN) exploded, inflamed and part of the ACN ended up in the sewage system of the village of Wetteren. More than 2000 ...
One Health research and training and government support for One Health in South Asia.
advocacy, funding, training, and technical support have been provided to South Asian countries to strengthen One Health (OH) collaborative approaches for controlling diseases with global human pandemic ...