A targeted proteomics method to detect urinary biomarkers of kidney disease

Last updated on 9-4-2021 by Jill Alexandre

Public Access



Acute and chronic kidney diseases are associated with an increased morbidity and mortality. Acute kidney injury (AKI) is a major clinical problem frequently encountered among intensive care unit patients while chronic kidney disease (CKD) affects up to 13% of the general population with high risk of progression to end-stage renal disease. Traditional markers currently used for diagnosis such as serum creatinine, display poor sensitivity and specificity, because they are influenced by several non-renal factors such as age, race and muscle mass. An accurate detection of kidney damage is cruci…

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