Biosafety risk assessment and management of laboratory-derived influenza A (H5N1) viruses transmissible in ferrets

Last updated on 22-8-2019 by Anonymous (not verified)

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Highly pathogenic avian influenza (HPAI) A (H5N1) viruses occasionally infect humans, but currently do not transmit efficiently among them. However, the risk for human pandemic influenza is a major concern should these viruses acquire the capacity for human-to-human transmission and retain their current virulence. Recently, two research teams have succeeded in modifying HPAI A (H5N1) viruses in such a way that they could be efficiently transmitted by respiratory route between ferrets, the experimental model for studying influenza virus transmission. In this article, the authors dis…

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