Humoral, cell-mediated and mucosal immunity induced by oculo-nasal vaccination of one-day-old SPF and conventional layer chicks with two different live Newcastle disease vaccines.

Last updated on 15-8-2023 by Anonymous (not verified)

Peer reviewed scientific article



To further characterize the immune response elicited by two live Newcastle disease vaccines, humoral, cellular and mucosal immunity was evaluated after oculo-nasal vaccination of day-old chickens. The preferential replication sites for each vaccine strain were investigated by screening different tissues using quantitative real-time reverse transcription-polymerase chain reaction (QRRT-PCR). The interference of maternally derived antibody with vaccination was also considered in conventional layer chickens. In SPF chickens, similar humoral immune-response was measured in blood and tears but a…

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