Indications for the presence of sulfate esters as considerable metabolites of sunset yellow FCF and orange GGN in rat faeces

Last updated on 23-8-2019 by Anonymous (not verified)

Public Access


Peer reviewed scientific article


Male Wistar rats received by stomach intubation 500 mg/kg of the azo dyes Sunset Yellow FCF and Orange GGN. Previous work revealed that in the Sunset Yellow FCF as well as in the Orange GGN aqueous faeces extracts a considerable orange metabolite is present, eluting as a strong peak before the unchanged dye after ion-pair reverse-phase liquid chromatography (RP-IP-HPLC). Incubation of both aqueous faeces extracts with arylsulphatase followed by high-performance liquid chromatography (HPLC) analysis, resulted in a significant orange metabolite peak height decrease together with a noticeable …

Associated health topics:

QR code

QR code for this page URL