Iron-induced oxidative stress in haemodialysis patients: a pilot study on the impact of diabetes98

Last updated on 23-8-2019 by Anonymous (not verified)

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Peer reviewed scientific article


BACKGROUND: Administration of intravenous iron preparations in haemodialysis patients may lead to the appearance of non-transferrin bound iron which can catalyse oxidative damage. We investigated this hypothesis by monitoring the oxidative stress of haemodialysis patients and the impact of iron and diabetes mellitus herein. MATERIALS AND METHODS: Baseline values of serum iron and related proteins, transferrin glycation, non-transferrin bound iron, antioxidant capacity and lipid peroxidation (malondialdehyde) of 11 haemodialysis patients (six non-diabetic and five type 2 diabetes) were compa…

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