Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing

Last updated on 23-8-2019 by Anonymous (not verified)

Public Access

Published

Keywords

Abstract:

After a pandemic wave in 2009 following their introduction in the human population, the H1N1pdm09 viruses replaced the previously circulating, pre-pandemic H1N1 virus and, along with H3N2 viruses, are now responsible for the seasonal influenza type A epidemics. So far, the evolutionary potential of influenza viruses has been mainly documented by consensus sequencing data. However, like other RNA viruses, influenza A viruses exist as a population of diverse, albeit related, viruses, or quasispecies. Interest in this quasispecies nature has increased with the development of next generation se…

Associated health topics:

QR code

QR code for this page URL