Treatment of a dog with an insulinoma-related peripheral polyneuropathy with corticosteroids.

Last updated on 23-8-2019 by Anonymous (not verified)

Peer reviewed scientific article



A crossbreed dog with a history of a chronic progressive tetraparesis had an insulinoma-related peripheral polyneuropathy. Frequent feeding and treatment with corticosteroids resulted in recovery from a non-ambulatory to an almost completely normal clinical state, despite the persistence of hypoglycaemia and hyperinsulinism. After euthanasia for uncontrollable seizures, the presence of a beta-cell carcinoma of the pancreas and extensive axonal degeneration of the peripheral nerves was confirmed by histopathological examination. These findings may indicate an immune-mediated pathogenesis for…

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