In vitro toxicity, genotoxicity and antigenotoxicity of Nigella sativa extracts from different geographic locations

Last updated on 11-12-2019 by Jill Alexandre

Peer reviewed scientific article




Nigella sativa or black cumin is used as a spice and as a natural remedy against a great variety of illnesses. However, plants growing at different locations, i.e., coping with different environmental stress conditions, may have different contents of specialized compounds include alkaloids, flavonoids, and terpenoids. Therefore their properties and biological effects may be different. We used the neutral red uptake test, the bacterial Vitotox and Ames assays and the micronucleus and comet tests in human C3A cells to investigate the in vitro cytotoxicity, genotoxicity and antigenotoxicity…

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