Search results - 29 results
Differential infection behavior of African swine fever virus (ASFV) genotype I and II in the upper respiratory tract.
genotype II strain BEL18 than genotype I strain E70 in the epithelial cell layer, (ii) a preference of ASFV infection for the lamina propria and a tropism of ASFV for various susceptible cell types in ...
In vitro and in vivo local tolerability of a synergistic anti-tuberculosis drug combination intended for pulmonary delivery.
Nathalie Source: J Appl Toxicol, Volume 43, Issue 2 (2023) Keywords: Alveolar Epithelial Cells Animals Antitubercular Agents Bronchoalveolar Lavage Fluid Humans Lung mice Mycobacterium tuberculosis Orlistat ...
Agglomeration of titanium dioxide nanoparticles increases toxicological responses in vitro and in vivo
composed of small or large agglomerates with similar dispersion medium composition. For in vitro testing, human bronchial epithelial (HBE), colon epithelial (Caco2) and monocytic (THP-1) cell lines were ...
Is aggregated synthetic amorphous silica toxicologically relevant?
size distributions. Their effect on cell metabolic activity, cell viability, epithelial barrier integrity, total glutathione content and, IL-8 and IL-6 secretion were investigated after 24 h exposure in ...
Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice
epithelial cells. Lung inflammation, acute phase response and genotoxicity were assessed 1, 3, and 28 days after a single intratracheal instillation of adult female C57BL /6 J BomTac mice. The doses were 6, 18 ...
Detection and Molecular Characterization of Foot and Mouth Disease Viruses from Outbreaks in Some States of Northern Nigeria 2013-2015.
vaccines and risk-based analysis resulting from insufficient data on the circulating FMD virus (FMDV) serotypes/strains. In 2013-2015, blood and epithelial samples were collected from reported FMD outbreaks ...
Immediate referral to colposcopy versus cytological surveillance for low-grade cervical cytological abnormalities in the absence of HPV test: A systematic review and a meta-analysis of the literature.
Paraskevaidis, Evangelos; M. Arbyn Source: Int J Cancer, Volume 140, Issue 1, p.216-223 (2017) Keywords: Atypical Squamous Cells of the Cervix Colposcopy Cytodiagnosis Disease Management Female Humans Population ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
carcinogenicity evaluating two human in vitro assays: hepatoma-derived cells and hTERT-immortalized renal proximal tubule epithelial cells, representing liver and kidney as major target organs. Cellular systems ...
Oxidative stress pathways involved in cytotoxicity and genotoxicity of titanium dioxide (TiO2) nanoparticles on cells constitutive of alveolo-capillary barrier in vitro.
microvascular cells were sensitive to endogenous redox changes and underwent apoptosis, but not alveolar epithelial A549 cells. Genotoxic potential of titanium dioxide nanoparticles was investigated using the ...
Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions.
triage Uterine Cervical Neoplasms Vaginal Smears Abstract: BACKGROUND: Atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intra-epithelial lesions (LSIL) are minor lesions ...