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Towards a more effective REACH legislation in protecting human health.
is required. Fast toxicology battery testing and toxicokinetic testing could improve speed of decision-making. Hereby, several improvements have been proposed that could improve the current REACH ...
Risk to human health related to the presence of perfluoroalkyl substances in food
https://www.sciensano.be/en/biblio/risk-human-health-related-presence-perfluoroalkyl-substances-food
animals, toxicokinetics and observed concentrations in human blood, the CONTAM Panel decided to perform the assessment for the sum of four PFAS s: PFOA, PFNA, PFH xS and PFOS. These made up half of the lower ...
Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens
Toxicology, Volume 141 (2020) Abstract: A comprehensive toxicokinetic analysis of citrinin (CIT) revealed interspecies differences for all toxicokinetic parameters and in absolute oral bioavailability. Oral ...
Risk assessment of chlorinated paraffins in feed and food
weights in male and female rats for SCCP s and MCCP s, respectively. For LCCP s, a reference point relevant for humans could not be identified. Due to the limitations in the toxicokinetic and toxicological ...
Citrinin: Occurrence, Oral Bioavailability & toxicokinetics in a porcine animal model
Publication Type: Scientific poster, presentation or proceeding Authors: Emmanuel Tangni Source: 41th Mycotoxin Workshop, Lisbon- Portugal (2019) Service: Contaminants organiques et additifs Organische contaminanten en additieven Organic contaminants and ...
Insights into In Vivo Absolute Oral Bioavailability, Biotransformation, and Toxicokinetics of Zearalenone, α-Zearalenol, β-Zearalenol, Zearalenone-14-glucoside, and Zearalenone-14-sulfate in Pigs
Uhlig; Marthe De Boevre; S. De Saeger; Ronette Gehring; Devreese, Mathias; Croubels, Siska Source: Journal of Agricultural and Food Chemistry, Volume 67, Issue 12 (2019) Keywords: Pig toxicokinetics ...
Risk to human and animal health related to the presence of 4,15-diacetoxyscirpenol in food and feed
was available on toxicity and on toxicokinetics in experimental and farm animals. Due to the limitations in the available data set, human acute and chronic health-based guidance values (HBGV) were ...
Short-term biodistribution and clearance of intravenously administered silica nanoparticles
hours, silicon was mainly excreted through urine. Further studies are necessary to evaluate the toxicokinetics of different types of silica nanomaterials at lower exposure doses in order to be able to ...
Toxicology of silica nanoparticles: an update
(particularly colloidal and stöber) induced toxicity via mechanisms similar to crystalline silica. In vivo, route of administration and physico-chemical properties of SiNPs influences the toxicokinetics. Adverse ...
Scientific Statement on Presence of microplastics and nanoplastics in food, with particular focus on seafood
toxicokinetic data are lacking for both microplastics and nanoplastics for a human risk assessment. It is recommended that analytical methods should be further developed for microplastics and developed for ...