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Risk to human health related to the presence of perfluoroalkyl substances in food

animals, toxicokinetics and observed concentrations in human blood, the CONTAM Panel decided to perform the assessment for the sum of four PFAS s: PFOA, PFNA, PFH xS and PFOS. These made up half of the lower ...

Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens

Toxicology, Volume 141 (2020) Abstract: A comprehensive toxicokinetic analysis of citrinin (CIT) revealed interspecies differences for all toxicokinetic parameters and in absolute oral bioavailability. Oral ...

Risk assessment of chlorinated paraffins in feed and food

weights in male and female rats for SCCP s and MCCP s, respectively. For LCCP s, a reference point relevant for humans could not be identified. Due to the limitations in the toxicokinetic and toxicological ...

Citrinin: Occurrence, Oral Bioavailability & toxicokinetics in a porcine animal model

Publication Type: Scientific poster, presentation or proceeding Authors: Emmanuel Tangni Source: 41th Mycotoxin Workshop, Lisbon- Portugal (2019) Service:  Contaminants organiques et additifs Organische contaminanten en additieven Organic contaminants and ...

Risk to human and animal health related to the presence of 4,15-diacetoxyscirpenol in food and feed

was available on toxicity and on toxicokinetics in experimental and farm animals. Due to the limitations in the available data set, human acute and chronic health-based guidance values (HBGV) were ...

Short-term biodistribution and clearance of intravenously administered silica nanoparticles

hours, silicon was mainly excreted through urine. Further studies are necessary to evaluate the toxicokinetics of different types of silica nanomaterials at lower exposure doses in order to be able to ...

Toxicology of silica nanoparticles: an update

(particularly colloidal and stöber) induced toxicity via mechanisms similar to crystalline silica. In vivo, route of administration and physico-chemical properties of SiNPs influences the toxicokinetics. Adverse ...

Scientific Statement on Presence of microplastics and nanoplastics in food, with particular focus on seafood

toxicokinetic data are lacking for both microplastics and nanoplastics for a human risk assessment. It is recommended that analytical methods should be further developed for microplastics and developed for ...

Scientific opinion on the Acute health risks related to the presence of cyanogenic glycosides in raw apricot kernels and products derived from raw apricot kernels

for toxicokinetic and of 3.16 to account for toxicodynamic inter-individual differences. In the absence of consumption data and thus using highest intakes of kernels promoted (10 and 60 kernels/day for ...

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