Search results - 33 results

Evaluation of an interferon-gamma release assay for early detection of lumpy skin disease virus infection and vaccination in cattle.

This assay overcomes the downsides of currently available immunoassays, and these results encourage its further evaluation. Health Topics:  Animal health Santé animale Diergezondheid Manuscript ...

Applicability of the DPRA on mixture testing: challenges and opportunities.

Keywords: Animal Testing Alternatives Animals Peptides Abstract: The in chemico direct peptide reactivity assay (DPRA) is validated to assess protein reactivity of chemical compounds, relating to the ...

Rational arguments for regulatory acceptance of consistency testing: benefits of non-animal testing over release testing of vaccines.

Issue 1, Number 377 (2023) Abstract: INTRODUCTION: There are rational arguments to replace existing in vivo potency and safety assays for batch release testing of vaccines with more advanced non-animal ...

Quantitative decision making in animal health surveillance: Bovine Tuberculosis Surveillance in Belgium as case study.

identify sustainable alternatives, which substantiate a bTB-free claim while ensuring early detection and acceptance by various animal health stakeholders. For this pupose, a stochastic iteration model was ...

Detection of Clinical and Subclinical Lumpy Skin Disease Using Ear Notch Testing and Skin Biopsies.

subclinical animals. Health Topics:  Animal health Santé animale Diergezondheid Manuscript versions:  DOI:  https://doi.org/10.3390/microorganisms9102171 File:  Version:  Published Full text access:  Public Access Full ...

Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.

Antoine Francotte; Paul Stickings Source: Biologicals, Volume 71 (2021) Keywords: Animal Testing Alternatives Animals Antibodies, Monoclonal Immunoassay Tetanus Tetanus Toxoid Vaccine Potency Abstract: ...

Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide

8, Issue 2 (2021) Abstract: Since the evaluation of nanomaterial (NM) hazards by animal testing is expensive, time-consuming and critical from an ethical point of view, much interest is being given to ...

A more sensitive, efficient and ISO 17025 validated Magnetic Capture real time PCR method for the detection of archetypal Toxoplasma gondii strains in meat.

the diagnosis of toxoplasmosis. Whereas serological tests are useful to prove contact with the parasite has occurred, the actual presence of the parasite in the tissues of a seropositive animal is not ...

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.

to implement testing of human in vitro alternatives to animal testing. Health Topics:  Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories Category:  A1 ...

Post-exposure Treatment with Anti-rabies VHH and Vaccine Significantly Improves Protection of Mice from Lethal Rabies Infection.

8, p.e0004902 (2016) Keywords: Animals Antibodies, Neutralizing Antibodies, Viral Cell Line Disease Models, Animal Female Half-Life Humans mice Neutralization Tests Post-Exposure Prophylaxis Rabies ...

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