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Healthy all life long- brochure on Sciensano's activities

Publication Type: Popular-science publication (vulgarising publication) Authors: Sciensano Source: Sciensano, Brussels (2018) Keywords: activities brochure Sciensano Health Topics:  Animal health ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

Adjuvants, Immunologic Animals Antigens, Bacterial Cell Wall Humans Immunity, Innate Lectins, C-Type Models, Animal Mycobacterium Pathogen-Associated Molecular Pattern Molecules Protein Binding Signal ...

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.

to implement testing of human in vitro alternatives to animal testing. Health Topics:  Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories Category:  A1 ...

In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics.

information. In the EU, dermal absorption has to be assessed in vitro since the Cosmetic Regulation 1223/2009/ EC forbids the use of animals. To obtain human-relevant data, a Franz diffusion cell protocol was ...

General considerations on the biosafety of virus-derived vectors used in gene therapy and vaccination.

p.385-94 (2013) Keywords: Animals Clinical Trials as Topic Genetic Therapy Genetic Vectors Hazardous Substances Humans Organisms, Genetically Modified Risk Assessment Vaccination Viruses Abstract: This ...

Implementation of the serological method for the potency testing for acellular Pertussis vaccine: user's view.

Publication Type: Scientific poster, presentation or proceeding Authors: F Ribaucour Source: Alternatives to animal testing, NA, Issue European Directorate for the Quality of Medicines & ...

Establishment of single dilution assays for animal based potency determinations

Publication Type: Scientific poster, presentation or proceeding Authors: Geneviève Waeterloos; L. Tesolin; F Ribaucour; Laurence Delbrassinne Source: WHO Webinar: Establishment of a single dilution potency assay (2020) Health Topics:  Effectiveness and sa ...

Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production

medium suffer from variability, lack of sensitivity, and/or require specific antibodies. In accordance with the consistency approach and the three Rs (3Rs), both aiming to reduce the use of animals for ...

Panel discussion on the adoption of 3Rs and non-animal approaches for quality control and batch release testing of these products

Publication Type: Scientific poster, presentation or proceeding Authors: Geneviève Waeterloos Source: https://www.nc3rs.org.uk/events/nc3rs-workshop-implementing-3rs-who-guidelines-understanding-impact-quality-control-and, https://www.nc3rs.org.uk/, Virtu ...

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