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Strain-level characterization without culture enrichment? Easing and accelerating outbreak investigation using shotgun metagenomics facilitated with nanopore adaptive sampling

resolved. Shotgun metagenomics is a sequencing method involving the analysis of the genetic material directly extracted from a sample, without the need for an isolation of the bacteria. By sequencing and ...

Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance.

exploring mutational effects in highly diverse Influenza A (H3N2) strains through considering the viral genetic background by using phylogenetic classification to stratify the samples. This resulted in ...

Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.

Keersmaecker Source: Int J Mol Sci, Volume 21, Issue 15 (2020) Keywords: Betacoronavirus Coronavirus Infections Databases, Genetic Genome, Viral Humans Open Reading Frames Pandemics Pneumonia, Viral ...

Public microbial resources centres: key hubs for FAIR microorganisms and genetic materials.

microbiology, microbial domain biological resource centres (mBRCs) have a long-standing experience in preserving and distributing authenticated microbial strains and genetic materials (e.g., recombinant plasmids, ...

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