Search results - 16 results
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
methodologies (NAM s) to identify molecular events underlying the genotoxic mode of action of chemicals. Previously, we developed the GENOMARK biomarker, consisting of 84 genes selected based on whole genomics ...
Development of a portable on-site applicable metagenomic data generation workflow for enhanced pathogen and antimicrobial resistance surveillanceAbstract
genomica Transversal activities in applied genomics Manuscript versions: DOI: https://sciensano.be/en/10.1038/s41598-023-46771-z File: Version: Published Full text access: Public Access Full text ...
Comparison of 6 DNA extraction methods for isolation of high yield of high molecular weight DNA suitable for shotgun metagenomics Nanopore sequencing to detect bacteriaAbstractBackgroundResultsConclusion
Publication Type: Peer reviewed scientific article Authors: Mathieu Gand; Bram Bloemen; Kevin Vanneste; Nancy Roosens; Sigrid C.J. De Keersmaecker Source: BMC Genomics, Volume 24, Issue 1 (2023) ...
Detection and identification of authorized and unauthorized GMOs using high-throughput sequencing with the support of a sequence-based GMO database
–veiligheid Santé et environnement Gezondheid en milieu Service: Activités transversales en génomique appliquée Transversale activiteiten in toegepaste genomica Transversal activities in applied genomics ...
Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants
silico approach. Previously, we reported some mismatches between the oligonucleotides of publicly available RT-qPCR assays and SARS-CoV-2 genomes collected from GISAID and NCBI, potentially impacting ...
Use of Whole Genome Sequencing Data for a First in Silico Specificity Evaluation of the RT-qPCR Assays Used for SARS-CoV-2 Detection.
Keersmaecker Source: Int J Mol Sci, Volume 21, Issue 15 (2020) Keywords: Betacoronavirus Coronavirus Infections Databases, Genetic Genome, Viral Humans Open Reading Frames Pandemics Pneumonia, Viral ...
Genome Editing in Agriculture: Methods, Applications, and Governance—A paper in the series on The Need for Agricultural Innovation to Sustainably Feed the World by 2050
(CAST), Volume 60, Issue 60 (2018) Abstract: Genome editing is the process of making precise, targeted sequence changes in the deoxyribonucleic acid of living cells and organisms. Recent advances have made ...
Comparison of SNP-based subtyping workflows for bacterial isolates using WGS data, applied to Salmonella enterica serotype Typhimurium and serotype 1,4,[5],12:i:.
Salmonella; Salmonella enterica; Salmonella typhimurium; SNP; subtyping; whole genome sequencing Abstract: Whole genome sequencing represents a promising new technology for subtyping of bacterial pathogens. ...
A molecular approach for the rapid, selective and sensitive detection of Exophiala jeanselmei in environmental samples: development and performance assessment of a real-time PCR assay
selectivity (100 %), PCR efficiency (95.5 %), dynamic range and repeatability of this qPCR assay were subsequently evaluated. The limit of detection for this qPCR assay was determined to be 1 copy of genomic ...
Development of giant bacteriophage phiKZ is independent of the host transcription apparatus
RNA Polymerases electronic Enzymes enzymology Functional gene Gene Expression Regulation,Viral Genes Genetic genetics Genome Genome,Viral growth & development Host-Pathogen Interactions im INFECTION ...