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A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds.
Publication Type: Peer reviewed scientific article Authors: Annebel De Vleeschauwer; David Lefebvre; Willems, T; Paul, G; Billiet, A; Murao, L E; Neyts, J; Goris, N; Kris De Clercq Source: ...
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
Palma, Armando M; Tanchis, Federica; Goris, Nesya; Lefebvre, David; Kris De Clercq; Leyssen, Pieter; Lacroix, Céline; Pürstinger, Gerhard; Coutard, Bruno; Canard, Bruno; Boehr, David D; Arnold, Jamie J; ...
A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.
Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Annebel De Vleeschauwer; Goris, Nesya; Van Borm, Steven; Chimirri, Alba; Monforte, Anna Maria; Valdazo-Gonzalez, Begona; ...
Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.
Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Annebel De Vleeschauwer; Goris, N; Kollanur, D; Billiet, A; Murao, L; Neyts, J; Kris De Clercq Source: Transbound Emerg ...
In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.
Johan; Goris, Nesya Source: Antiviral Res, Volume 105, p.59-63 (2014) Keywords: Animals Antiviral Agents Aphthovirus Benzimidazoles Cattle Cell Line Chlorocebus aethiops Cytidine Cytopathogenic Effect, ...
Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.
Publication Type: Peer reviewed scientific article Authors: van der Linden, Lonneke; Ulferts, Rachel; Nabuurs, Sander B; Kusov, Yuri; Liu, Hong; George, Shyla; Lacroix, Céline; Goris, Nesya; ...
Characteristics of serology-based vaccine potency models for foot-and-mouth disease virus.
Publication Type: Peer reviewed scientific article Authors: Willems, Tom; David Lefebvre; Goris, Nesya; Diev, Vyacheslav I; Kremenchugskaya, Svetlana R; Paul, Guntram; Haas, Bernd; Kris De Clercq ...
Confidence in indirect assessment of foot-and-mouth disease vaccine potency and vaccine matching carried out by liquid phase ELISA and virus neutralization tests.
Fondevila, Norberto; Palma, Eduardo; Goris, Nesya; Kris De Clercq; Mattion, Nora Source: Vaccine, Volume 28, Issue 38, p.6235-41 (2010) Keywords: Animals Cattle Cattle Diseases Cell Line Cricetinae Cross ...
Limited genetic diversity and gene expression differences between egg- and non-egg-related Salmonella Enteritidis strains36855
Publication Type: Peer reviewed scientific article Authors: N Botteldoorn; E. Van Coillie; Goris,J.; Werbrouck,H.; Piessens,V.; Godard,C.; Scheldeman,P.; Herman,L.; Heyndrickx,M. Source: ...
Modulating mouse innate immunity to RNA viruses by expressing the Bos taurus Mx system.
Publication Type: Peer reviewed scientific article Authors: Garigliany, M-M; Cloquette, K; Mathias Leroy; Decreux, A; Goris, N; Kris De Clercq; Desmecht, D Source: Transgenic Res, Volume 18, Issue ...