Search results - 4 results
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
assessment. In addition, the developed qPCR array was able to provide additional information on compounds for which so far debatable genotoxicity data are available. The results indicate that the new in vitro ...
Coatings in food contact materials: Potential source of genotoxic contaminants?
the substances, additional toxicological information is needed. Health Topics: Food contact materials Service: Évaluation des risques et de l'impact sur la santé Risico- en ...
(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
a case study. By applying our strategy, 106 out of the 1723 substances were assigned ‘high priority’ as they were predicted mutagenic by 4 different (Q) SAR models. Information provided within the models ...
Evaluation of the potential health risks of substances migrating from polycarbonate replacement baby bottles.
substances was shown to be below their SML. The unlisted substances were evaluated using toxicological information from previous evaluations, or if not available, by applying the Threshold of Toxicological ...