Search results - 6 results
Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.
printed paper and board food contact material (FCM) substances for further in-depth safety evaluation. Within the strategy, focus was put on genotoxicity, a key toxicological endpoint when evaluating ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
Toxicology of silica nanoparticles: an update
selected and sorted based on in vitro and in vivo studies: to provide an update on SiNPs toxicity and to address the knowledge gaps indicated in the review of Napierska (Part Fibre Toxicol 7:39, 2010). ...
Toxicity and biological responses (in vitro) influenced by aggregation and agglomeration of manufactured nanomaterials
Source: Toxicology Letters, Volume 280 (2017) Health Topics: Nanomaterials Nanomaterialen Nanomatériaux Service: Éléments traces et nanomatériaux Spoorelementen en nanomaterialen Trace elements and ...
In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics.
Source: Skin Pharmacol Physiol, Volume 29, Issue 6, p.300-308 (2016) Keywords: Adult Drug and Narcotic Control Female Humans Hydroquinones In Vitro Techniques Male middle aged Reproducibility of Results ...
Investigation of the genotoxicity of substances migrating from polycarbonate replacement baby bottles to identify chemicals of high concern.
Chemicals Agency (ECHA), in silico prediction tools (ToxTree and Derek Nexus(TM)) and the in vitro Vitotox(®) test for detecting DNA damage. By applying the decision tree, substances could be classified into ...