Search results - 66 results

In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Viral Drug Discovery Foot-and-Mouth Disease Models, Theoretical Oximes Ribavirin RNA, Viral Sulfonamides Virus Cultivation Virus Replication Abstract: Foot-and-mouth disease virus (FMDV) is a highly ...

Bluetongue, Schmallenberg- what is next? Culicoides-borne viral diseases in the 21st Century.

diverse backgrounds in vector ecology, epidemiology, entomology, virology, animal health, modelling, and genetics. Here, we report on the key findings of this workshop. Health Topics:  Animal health Santé ...

Efficacy of marker vaccine candidate CP7_E2alf against challenge with classical swine fever virus isolates of different genotypes.

these strains, efficacy was assessed after single oral vaccination of wild boar and single intramuscular vaccination of domestic pigs using challenge models with recent CSFV strains and the highly ...

Setting up a SPF chicken model for the pathotyping of West Nile virus (WNV) strains.

of these genetically variable isolates is not well characterized for birds. Therefore, we investigated whether SPF chickens could be a valuable avian model for the pathotyping of WNV strains. ...

The origin of biased sequence depth in sequence-independent nucleic acid amplification and optimization for efficient massive parallel sequencing.

biased sequence depth when using random amplification. Avian paramyxovirus type 8 was used as a model RNA virus to investigate these mechanisms. We showed, based on in silico analysis of the sequence depth ...

In vitro and in vivo infectious potential of coxiella burnetii: a study on Belgian livestock isolates.

vitro (human HeLa and bovine macrophage cells) and in vivo (BALB /c mice) models. The isolates had distant genomic profiles with one–the goat isolate–being identical to the predominant strain circulating ...

Proteomic characterization of murid herpesvirus 4 extracellular virions.

neoplastic diseases. As EBV and KSHV are host-range specific and replicate poorly in vitro, animal counterparts such as Murid herpesvirus-4 (MuHV-4) have been widely used as models. In this study, we used ...

Clinical pattern characterization of cattle naturally infected by BTV-8.

positive until the end of the study. These results should ensure more accurate detection of an emerging infectious disease and are of prime importance in improving the modelling of BTV-8 persistence ...

An essential role for γ-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle.

lymphoproliferative disease occurs after a prolonged asymptomatic incubation period after transmission. Our recent findings with the rabbit model indicated that AlHV-1 infection is not productive during MCF. Here, we ...

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