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Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.
mice Mice, Inbred C57BL Mice, Knockout T-Lymphocytes, Cytotoxic Tuberculosis Vaccines Vaccination Vaccines, DNA Abstract: Reactivation tuberculosis (TB) is a serious problem in immunocompromised ...
Mycobacterium tuberculosis with disruption in genes encoding the phosphate binding proteins PstS1 and PstS2 is deficient in phosphate uptake and demonstrates reduced in vivo virulence.
Huygen, Kris; Content, Jean Source: Infect Immun, Volume 73, Issue 3, p.1898-902 (2005) Keywords: Animals Bacterial Proteins Culture Media Gene Deletion Humans mice Mice, Inbred BALB C Mice, Inbred C57BL ...
Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.
Histocompatibility Antigen H-2D Interferon-gamma Interleukin-2 mice Mice, Inbred C57BL Molecular Sequence Data Mycobacterium tuberculosis T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccines Vaccines, DNA ...
Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.
Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium bovis Mycobacterium tuberculosis Peptides Abstract: We previously demonstrated that Bacillus Calmette-Guerin (BCG) immunization activated D(b) ...
CD4+ T cells contain Mycobacterium tuberculosis infection in the absence of CD8+ T cells in mice vaccinated with DNA encoding Ag85A.
p.2455-9 (2000) Keywords: Animals Antigens, Bacterial BCG Vaccine beta 2-Microglobulin CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes Interferon-gamma mice Mice, Inbred BALB C Mice, Inbred C57BL ...
Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by Bacillus Calmette-Guérin vaccination in H-2b mice.
CD8-Positive T-Lymphocytes Cell Line Chloroquine Culture Media H-2 Antigens Interferon-gamma Lymphocyte Activation Membrane Glycoproteins mice Mice, Inbred C57BL Perforin Pore Forming Cytotoxic Proteins ...
Cross-reactive immune responses against Mycobacterium bovis BCG in mice infected with non-tuberculous mycobacteria belonging to the MAIS-Group.
BALB C Mice, Inbred C57BL Mycobacterium Mycobacterium avium Mycobacterium avium Complex Mycobacterium scrofulaceum Spleen Th1 Cells Abstract: Two bacillus Calmette-Guérin (BCG)-susceptible mouse strains, ...
Induction of immunity by DNA vaccination: application to influenza and tuberculosis.
Immunity, Cellular Influenza A virus Influenza Vaccines Lymphocyte Activation mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Nucleoproteins RNA-Binding Proteins Spleen T-Lymphocytes, ...
Immunogenicity and protective efficacy of a tuberculosis DNA vaccine.
Bacterial BCG Vaccine Cytokines Disease Models, Animal DNA, Bacterial Immunity, Cellular mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis T-Lymphocytes Tuberculosis Tumor Cells, Cultured ...