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Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting.
Interferon-gamma Interleukin-2 mice Vaccination Vaccines, DNA Abstract: C57BL /6 mice were vaccinated with plasmid DNA encoding Ag85 from Mycobacterium tuberculosis, with Ag85 protein in adjuvant, or with a combined ...
Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment.
In BALB /c mice, gg immunization could induce elevated antibody and cytotoxic T lymphocyte responses with plasmid doses 50-fold lower than those required for i.m. immunization. Interleukin-2 (IL-2) and ...
Cloning of the gene encoding a 22-kilodalton cell surface antigen of Mycobacterium bovis BCG and analysis of its potential for DNA vaccination against tuberculosis.
in the bacterial cell wall and membrane compartment but not in the cytosol. C57BL /6, C3H, and BALB /c mice were vaccinated with plasmid DNA encoding the 22-kDa protein and analyzed for immune response ...
Immunogenicity and efficacy of a tuberculosis DNA vaccine encoding the components of the secreted antigen 85 complex.
Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium bovis T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccines, DNA Abstract: BALB /c and C57BL /6 mice were injected intramuscularly with plasmid DNA ...