Search results - 134 results

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.

Publication Type: Peer reviewed scientific article Authors: David Lefebvre; Annebel De Vleeschauwer; Goris, Nesya; Van Borm, Steven; Chimirri, Alba; Monforte, Anna Maria; Valdazo-Gonzalez, Begona; King, Donald P; Neyts, Johan; Kris De Clercq Source: Bioch ...

Study of the virulence of serotypes 4 and 9 of African horse sickness virus in IFNAR(-/-), Balb/C and 129 Sv/Ev mice.

Interferon-alpha mice Mice, Inbred BALB C Mice, Knockout Receptor, Interferon alpha-beta RNA, Double-Stranded Serogroup virulence Abstract: African horse sickness virus (AHSV) is a double-stranded RNA virus which ...

Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.

Dis, Volume 61, Issue 6, p.e89-91 (2014) Keywords: Animals Antiviral Agents Cytidine Disease Models, Animal Foot-and-Mouth Disease Foot-and-Mouth Disease Virus mice Mice, SCID RNA, Viral Abstract: Recent ...

Dose-dependent effect of experimental Schmallenberg virus infection in sheep.

number of productively infected animals within each group, as evidenced by viraemia, seroconversion and viral RNA in the organs, depended on the inoculated dose, indicating that a critical dose has to be ...

False-positive results in metagenomic virus discovery: a strong case for follow-up diagnosis.

RNA, Viral specimen handling Viruses Abstract: A viral metagenomic approach using virion enrichment, random amplification and next-generation sequencing was used to investigate an undiagnosed cluster of ...

Schmallenberg virus circulation in culicoides in Belgium in 2012: field validation of a real time RT-PCR approach to assess virus replication and dissemination in midges.

Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Viral Virus Replication Abstract: Indigenous Culicoides biting midges are suggested to be putative vectors for the recently emerged Schmallenberg ...

In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Viral Drug Discovery Foot-and-Mouth Disease Models, Theoretical Oximes Ribavirin RNA, Viral Sulfonamides Virus Cultivation Virus Replication Abstract: Foot-and-mouth disease virus (FMDV) is a highly ...

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