Search results - 92 results

Regulatory workshop on challenge strain development and GMP manufacture- A stakeholder meeting report.

a significant challenge for developers. Still, it is preferred over reverse genetics challenge strains for several reasons, including implications and regulations around genetically modified organisms (GMO s). ...

Unlocking the genomic landscape: Results of the Beyond 1 Million Genomes (B1MG) pilot in Belgium towards Genomic Data Infrastructure (GDI)

Belgium Beyond 1 Million Genomes Genomic Data Infrastructure implementation Abstract: Abstract Genomic medicine has great potential to offer insights into how humans’ genetic variation can affect their ...

Genomic monitoring of SARS-CoV-2 variants using sentinel SARI hospital surveillance.

Issue 10 (2023) Keywords: COVID-19 Genomics hospitals Humans Pandemics Pneumonia SARS-CoV-2 Sentinel Surveillance Abstract: BACKGROUND: To support the COVID-19 pandemic response, many countries, including ...

Targeted Chromosomal Barcoding Establishes Direct Genotype-Phenotype Associations for Antibiotic Resistance in Mycobacterium abscessus.

Gonzalo-Asensio, Jesús Source: Microbiol Spectr (2023) Abstract: A bedaquiline-resistant Mycobacterium abscessus isolate was sequenced, and a candidate mutation in the gene was identified as responsible for the ...

High diversity of yeast species and strains responsible for vulvovaginal candidiasis in South-East Gabon.

Volume 33, Issue 2 (2022) Abstract: OBJECTIVES: Candida albicans generally remains the principal pathogenic yeast responsible for vulvovaginal candidiasis (VVC), although with variable prevalence. In this ...

Insights From Early Clinical Trials Assessing Response to mRNA SARS-CoV-2 Vaccination in Immunocompromised Patients.

lower response to the vaccine such as anti- CD19, anti- CD20 or anti- CD38 therapies, low (naive) CD4 T-cell counts, genetic or therapeutic Bruton tyrosine kinase deficiency, treatment with ...

Development of a data-intensive centralized system for surveillance and outbreak investigation of bacterial pathogens using whole-genome sequencing

were optimized for time-critical situations such as outbreaks, where providing a quick response facilitates efficient public health intervention, thereby minimizing the clinical and economic impact. ...

Frequency of Participation in External Quality Assessment Programs Focused on Rare Diseases: Belgian Guidelines for Human Genetics Centers.

Centers of Human Genetics. However, directives on the minimal frequency of participation in genetic quality control schemes are lacking or too heterogeneous, with a possible impact on health care quality. ...

Lentiviral vector induces high-quality memory T cells via dendritic cells transduction.

Biol, Volume 4, Issue 1 (2021) Keywords: Animals beta 2-Microglobulin CD8-Positive T-Lymphocytes Dendritic Cells Female genetic engineering Genetic Vectors Humans Immunity, Cellular Immunologic Memory ...

The Belgian DNA Debate: An Online Deliberative Platform on the Ethical, Legal, and Social Issues of Genomics

unfavourable effects such as psychological distress. The third theme covers the tension between a genomics-based responsibility and the rejection of genetic discrimination. The fourth theme depicts how genomic ...

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