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Evaluation of the clinical performance of the HPV-Risk assay using the VALGENT-3 panel.

within the VALGENT-3 panel, and to compare its performance to the clinically validated Hybrid Capture 2 assay (HC2). The VALGENT-3 panel comprises 1,300 consecutive samples from women participating in the ...

Defining optimal triage strategies for hrHPV screen positive women- an evaluation of HPV 16/18 genotyping, cytology and p16/Ki-67 cyto-immunochemistry.

61.7%, 68.3% and 85.0% for women with hrHPV+ clinician-taken samples. Respective specificities were 70.5%, 89.1% and 76.7%. The absolute accuracy of the triage tests was similar for women with a hrHPV+ ...

Introduction of liquid-based cytology and human papillomavirus testing in cervical cancer screening in Luxembourg.

METHODS: Between the first January 2013 and 31st December 2015, 315,868 cervical samples from 150,815 women (mean age 42.2 years) were investigated by the national cytology laboratory. Slides were prepared ...

Performance of a Cartridge-Based Assay for Detection of Clinically Significant Human Papillomavirus (HPV) Infection: Lessons from VALGENT (Validation of HPV Genotyping Tests).

performance. Through VALGENT, we assessed the performance of the cartridge-based Xpert HPV assay (Xpert HPV), which detects 14 high-risk (HR) types and resolves HPV16 and HPV18 /45. Samples from women attending ...

Direct comparison of two vaginal self-sampling devices for the detection of human papillomavirus infections.

Abstract: BACKGROUND AND OBJECTIVES: Two devices for vaginal self-sampling of dry cell material (Evalyn Brush, Rovers Medical Devices; Qvintip, Aprovix) were compared using the Abbott RealTime High Risk HPV ...

Clinical and analytical performance of the PapilloCheck HPV-Screening assay using the VALGENT framework.

context is essential, using well-annotated samples, such as those generated via the Validation of Genotyping Tests- HPV (VALGENT) framework. OBJECTIVE: Our aim was to assess the PapilloCheck HPV assay in ...

Analytical performance evaluation of Anyplex II HPV28 and Euroarray HPV for genotyping of cervical samples.

Genotypes 16, 18 or 45 than for the other 11 HPV s. The average number of HPV genotypes detected per sample was similar with 2.6 and 2.5, for Anyplex and EuroArray, respectively. In conclusion, Anyplex and ...

VALGENT: A protocol for clinical validation of human papillomavirus assays.

VALGENT involves the collation of fresh or archived cervical cell specimen from women attending routine screening supplemented with cytologically abnormal samples. Multiple aliquots of residual material are ...

Reaching women who do not participate in the regular cervical cancer screening programme by offering self-sampling kits: a systematic review and meta-analysis of randomised trials.

Offering devices for self-sampling has the potential to increase participation of hard-to-reach women. METHODS: A systematic review and meta-analysis were performed to evaluate the participation after an ...

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