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Towards a more effective REACH legislation in protecting human health.
Belleghem, Frank; Vanoirbeek, Jeroen; Van Larebeke, Nicolas Source: Toxicol Sci, Volume 199, Issue 2 (2024) Keywords: Animals Belgium environmental exposure Hazardous Substances Humans Risk Assessment Toxicity ...
Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.
environmental exposure Hazardous Substances Humans Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de l'impact sur la santé Risico- en ...
Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.
Cardiotoxicity environmental exposure Hazardous Substances Humans Health Topics: Health and environment Santé et environnement Gezondheid en milieu Manuscript versions: DOI: ...
The purity of tattoo inks, screening substances of high concern
implementing compound-specific restrictions. Methodology: A screening method based on LC-QqQ- MS was developed and validated for screening 40 substances of high concern in tattoo inks. An additional ...
NanoRegister Evaluation: "Compliance control and substantive evaluation of the registration of substances produced in nanoparticulate state according to Royal Decree of 27 May 2014”- Trade Year 2017
Publication Type: Sci. report, recommendat°, guidance doc., directive, monograph Authors: Stella Mathioudaki; Eveline Verleysen; Jan Mast Source: Sciensano/ SPF DG5 (2020) Keywords: compliance nanomaterials Nanoregister database Royal Degree of 27 May 201 ...
Biomarkers in patients admitted to the emergency department after exposure to acrylonitrile in a major railway incident involving bulk chemical material.
Abstract: BACKGROUND: A railway incident with victims of exposure to the cyanogenic substance acrylonitrile (ACN). AIMS: We retrospectively (i)built an inventory of the clinical characteristics of individuals ...
Dermal exposure of Belgian florists to insecticide residues
(4.8 and 21.9 mg/kg, respectively) measured on cut flowers. At the PDE 90th Percentile, 15 of 55 active substances exceed the AOEL indicating many at risk situations for florists. Clofentezine had the ...
The Vitotox and ToxTracker assays: a two-test combination for quick and reliable assessment of genotoxic hazards
chemical entities such as pharmaceutical and cosmetic substances. In a first tier a battery of regulatory accepted in vitro tests is recommended. These tests have a relatively high sensitivity, but a low ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Abstract: Prior to the downstream development of chemical substances, including pharmaceuticals and cosmetics, their influence on the genetic apparatus has to be tested. Several in vitro and in vivo assays ...
A survey of pesticide residues in cut flowers from various countries.
methods (GC- MS- MS and LC- MS- MS) in a laboratory accredited for pesticide residues. For all the samples analysed, a total of 97 active substances were detected, i.e. an average of 14 active substances ...