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Rational arguments for regulatory acceptance of consistency testing: benefits of non-animal testing over release testing of vaccines.
Issue 1, Number 377 (2023) Abstract: INTRODUCTION: There are rational arguments to replace existing in vivo potency and safety assays for batch release testing of vaccines with more advanced non-animal ...
Development and Validation of a New DIVA Real-Time PCR Allowing to Differentiate Wild-Type Lumpy Skin Disease Virus Strains, Including the Asian Recombinant Strains, from Neethling-Based Vaccine Strains.
difficulties to existing DIVA PCR tests, as these do not differentiate between homologous vaccine strains and the recombinant strains. We, therefore, developed and validated a new duplex real-time PCR capable of ...
The PARERE network in Belgium: increasing awareness on NAMs among regulators
Brussel/Bruxelles Environnement, Issue Leefmilieu Brussel/Bruxelles Environnement, Brussels, Belgium (2023) Keywords: 3Rs alternative methods animal testing EU Dir 2010/63 NAMs new approach methodologies PARERE ...
Progress of the RE-Place project
://leefmilieu.brussels/pro/milieubeheer/dierenwelzijn-garanderen/proefdieren-en-alternatieven-de-weg-vooruit Keywords: 3Rs Principle alternative methods to animal testing animal testing Database Knowledge sharing NAMs new approach methodologies RE-Place Service: Risques chimiques et physiques pour la santé ...
Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants.
inhibition assay allows the phenotypical identification of resistant strains; however, this test often has limited sensitivity with high variability depending on the virus strain, drugs and assays. Once ...
Pulmonary Aspergillosis in Humboldt Penguins—Susceptibility Patterns andMolecular Epidemiology of Clinical and Environmental Aspergillus fumigatus Isolates from a Belgian Zoo
3 (2023) Keywords: antifungal susceptibility testing Aspergillus fumigatus avian aspergillosis azole resistance cyp51A genotyping MIC microsatellite typing One Health Spheniscus humboldti Abstract: ...
Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples
emergence was observed slightly earlier, which suggests that wastewater sampling could be an early warning system and could be an interesting alternative to extensive human testing. Health Topics: ...
Substandard and falsified ivermectin tablets obtained for self‐medication during the COVID‐19 pandemic as a source of potential harmAbstract
Koenraad; Willocx, Marie Source: Drug Testing and Analysis (2023) Health Topics: Effectiveness and safety of vaccines, medicines and health products- Quality of medical laboratories Efficacité et sécurité ...
Challenges in Drug Surveillance: Strengthening the Analysis of New Psychoactive Substances by Harmonizing Drug Checking Services in Proficiency Testing.
towards drug checking services, proficiency testing was set up to evaluate existing analytical techniques and investigate the capability to correctly identify circulating NPS. Twenty blind substances, ...
Papilloplex HR-HPV test has non-inferior clinical performance for detection of human papillomavirus infection: assessment using the VALGENT framework.
Cervical Dysplasia Uterine Cervical Neoplasms Abstract: AIM: The Papilloplex high-risk human papillomavirus (hrHPV) test (Genefirst, Oxford, UK) is a single tube real-time HPV test which provides multiplex ...