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Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.
efficiently identify pollutants of interest. The evidence will be integrated in novel Adverse Outcome Pathways to facilitate regulatory acceptance of non-animal methods for cardiotoxicity testing. The current ...
EFSA Project on the use of New Approach Methodologies (NAMs) for the hazard assessment of nanofibres. Lot 1, nanocellulose oral exposure: gastrointestinal digestion, nanofibres uptake and local effects
submitted to a thorough physicochemical characterisation. A battery of in vitro tests was used to provide insight into NC hazard and mode of action according to a tiered approach, which lead to selection of ...
An AOP-based IATA to pave the way toward animal-free genotoxicity testing
Integrated approaches to testing and assessment (IATA) Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de l'impact sur la santé ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
towards a more human-relevant in vitro genotoxicity testing strategy without the use of experimental animals. Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: ...