Search results - 20 results
Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial.
tuberculosis Treatment Outcome Tuberculosis Tuberculosis Vaccines Young adult Abstract: BACKGROUND: HIV-1 infection is associated with increased risk of tuberculosis and a safe and effective vaccine would assist ...
M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.
Mutation Mycobacterium bovis Mycobacterium tuberculosis Mycolic Acids Organ Specificity Oxygen Species Specificity Spleen Th1 Cells Th17 Cells Trachea Treatment Outcome Tuberculosis Vaccination virulence ...
An update on vaccines for tuberculosis- there is more to it than just waning of BCG efficacy with time.
Trials, Phase I as Topic Clinical Trials, Phase II as Topic Humans Tuberculosis Tuberculosis Vaccines Abstract: INTRODUCTION: Apart from better diagnostics and new anti-microbial drugs, an effective vaccine ...
DNA vaccines against mycobacterial diseases.
Bacterial Vaccines Buruli Ulcer Humans Mycobacterium Paratuberculosis Tuberculosis Vaccines, DNA Abstract: Bacteria belonging to the genus Mycobacterium can cause several infectious diseases affecting humans ...
Immunogenicity and protective efficacy of tuberculosis subunit vaccines expressing PPE44 (Rv2770c).
Immunity, Cellular Immunotherapy, Adoptive mice Mice, Inbred Strains Molecular Sequence Data Mycobacterium tuberculosis Phylogeny RNA, Messenger Tuberculosis Vaccines Tuberculosis, Pulmonary Vaccines, DNA ...
Immunogenicity of eight dormancy regulon-encoded proteins of Mycobacterium tuberculosis in DNA-vaccinated and tuberculosis-infected mice.
Tuberculosis Tuberculosis Vaccines Vaccines, DNA Abstract: Hypoxia and low concentrations of nitric oxide have been reported to upregulate in vitro gene expression of 48 proteins of the dormancy (DosR) regulon ...
Immunogenicity and protective efficacy of tuberculosis DNA vaccines combining mycolyl-transferase Ag85A and phosphate transport receptor PstS-3.
Immunity, Cellular mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Plasmids Recombinant Fusion Proteins Th1 Cells Transfection Tuberculosis Tuberculosis Vaccines Vaccines, DNA Abstract: ...
Evaluation of the immunogenicity of pBudCE4.1 plasmids encoding mycolyl-transferase Ag85A and phosphate transport receptor PstS-3 from Mycobacterium tuberculosis.
Acyltransferases Animals ATP-Binding Cassette Transporters Bacterial Proteins Bacterial Vaccines Base Sequence DNA Primers Female mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Plasmids ...
Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.
mice Mice, Inbred C57BL Mice, Knockout T-Lymphocytes, Cytotoxic Tuberculosis Vaccines Vaccination Vaccines, DNA Abstract: Reactivation tuberculosis (TB) is a serious problem in immunocompromised ...
Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv.
Enzyme-Linked Immunosorbent Assay Immunization, Secondary Interferon-gamma Interleukin-17 mice Mice, Inbred BALB C Mycobacterium tuberculosis Survival Analysis T-Lymphocyte Subsets Tuberculosis Vaccines, DNA ...