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Regulatory issues regarding manufacture and control of vaccine adjuvants. The EU situation.

testing with the adjuvant alone and in combination with the antigen should be thoroughly studied and documented. Finally, regarding clinical studies, the inclusion of an adjuvant in a vaccine must always be ...

Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting.

Interferon-gamma Interleukin-2 mice Vaccination Vaccines, DNA Abstract: C57BL /6 mice were vaccinated with plasmid DNA encoding Ag85 from Mycobacterium tuberculosis, with Ag85 protein in adjuvant, or with a combined ...

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