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Environmental risk assessment of clinical trials involving modified vaccinia virus Ankara (MVA)-based vectors.

strain, which has been developed as a vaccine against smallpox, is since the nineties widely tested in clinical trials as recombinant vector for vaccination or gene therapy applications. Although MVA is ...

Testing chemical agents with the cytokinesis-block micronucleus cytome assay.

Humans Micronuclei, Chromosome-Defective Micronucleus Tests Mutagens Abstract: In order to evaluate the applicability of the cytokinesis-block micronucleus cytome assay in routine mutagenicity testing we ...

Determination of the volume-specific surface area by using transmission electron tomography for characterization and definition of nanomaterials.

definition of the examined gold and silica NM can benefit from application of conventional bright field electron tomography: the NM can be visualized in 3D, while surface features and the VSSA can be measured. ...

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