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Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.
toxicological evidence is needed. This protocol outlines a step-by-step framework for conducting this review. Using the National Toxicology Program (NTP) Health Assessment and Translation (HAT) approach for ...
EFSA Project on the use of New Approach Methodologies (NAMs) for the hazard assessment of nanofibres. Lot 1, nanocellulose oral exposure: gastrointestinal digestion, nanofibres uptake and local effects
submitted to a thorough physicochemical characterisation. A battery of in vitro tests was used to provide insight into NC hazard and mode of action according to a tiered approach, which lead to selection of ...
The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Carole Yauk; Stefaan Verhulst; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: Joint 3R Symposium 2023 (2023) Keywords: genotox ...
An AOP-based IATA to pave the way toward animal-free genotoxicity testing
Integrated approaches to testing and assessment (IATA) Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de l'impact sur la santé ...
Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.
environmental risk assessment oncolytic virus shedding Abstract: Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...
Occurrence of microcystin congeners in surface waters and food in Belgium as a source of exposure to humans
group worldwide, the microcystin congeners (MC s). After method validation, the quantitative UHPLC- MS / MS approaches were applied to Belgian samples to characterize potential human exposure sources in ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
genome copies). Finally, a targeting of the norovirus by hybridization capture enhanced the relative quantity of reads classified as norovirus but at the expense of using a less open approach that can only ...
A Multifaceted Approach for Evaluating Hepatitis E Virus Infectivity In Vitro: Cell Culture and Innovative Molecular Methods for Integrity Assessment
Publication Type: Peer reviewed scientific article Authors: Tatjana Locus; Lambrecht, Ellen; Sophie Lamoral; Willems, Sjarlotte; Steven Van Gucht; Vanwolleghem, Thomas; Michael Peeters Source: Veterinary Sciences, Volume 10, Issue 12 (2023) Health Topics: ...
Sentinel-2 Satellite and Hysplit Model Show that Local Cereal Harvesting Substantially Contributes to Peak Alternaria Spore Concentrations
estimate periods of peak Alternaria spore concentrations and sources at a continental scale. This approach can be replicated for other bioaerosols that affect human health, agriculture and forestry. Health ...