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Protocol for a systematic review and meta-analysis of the diagnostic test accuracy of host and HPV DNA methylation in cervical cancer screening and management.

methylation cut-off thresholds, and accuracy in high-risk HPV positive women. Our reference standard will be histology. We will perform meta-analyses using Cochrane guidelines for diagnostic test accuracy. We ...

Cervical cancer screening program and Human Papillomavirus (HPV) testing, part II: Update on HPV primary screening.

and more. A two-step triage scenario with twice cytology at cutoff ASC- US + offers a good balance of efficiency (4 to 9 referrals to detect one CIN3 +, ~40% of referral) and safety (risk of CIN3 + in ...

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