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Next-Generation Sequencing: An Eye-Opener for the Surveillance of Antiviral Resistance in Influenza

antivirals can lead to antiviral resistance mutations in the entire influenza genome. Therefore, the methods to detect these mutations should be developed and implemented. In this Opinion, we assess how NGS ...

Incorporation of the influenza A virus NA segment into virions does not require cognate non-coding sequences.

Volume 7 (2017) Keywords: INFLUENZA non coding regions Abstract: For each influenza virus genome segment, the coding sequence is flanked by non-coding (NC) regions comprising shared, conserved sequences ...

Overlapping signals for translational regulation and packaging of influenza A virus segment 2.

and replicated poorly, producing virions with elevated particle: PFU ratios. Analysis of the genome content of virus particles showed reduced packaging of the mutant segment 2 vRNAs. Overall, we ...

A general approach to identify low-frequency variants within influenza samples collected during routine surveillance.

Nancy Roosens; Kevin Vanneste Source: Microb Genom, Volume 8, Issue 9 (2022) Keywords: COVID-19 Genome, Viral Humans Influenza A Virus, H3N2 Subtype Influenza, Human SARS-CoV-2 Abstract: Influenza viruses ...

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