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Search results - 17 results

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...

Mixtures of genotoxicants: does the principle of additivity apply?

Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells

Source: EEMGS meeting, Malaga, Spain (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid ...

Development of an AOP-based IATA for genotoxicity

O Armant; C Pachoulide; H Bouwmeester; G Raitano; E Benfenati; E Wyrzykowska; M Stepnik; T Puzyn; M Audebert; Birgit Mertens Source: EEMGS meeting (2023) Keywords: adverse outcome pathways genotoxicity ...

The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment

SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

GENOMARK, a promising new approach methodology for genotoxicity testing in the cosmetic industry

International cosmetic congress, Antalya, Turkey (2022) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation ...

Scientific opinion on the risk for public and animal health related to the presence of sterigmatocystin in food and feed

method methods mycotoxins,sterigmatocystin,food,feed,dietary exposure,genotoxic and carcinogenic,risk assessment need observed occurrence ON Pig Pigs Poultry public Quantification result results risk ...

Scientific opinion on emerging and novel brominated flame retardants (BFRs) in food

bioaccumulation potential. There is convincing evidence that tris(2,3-dibromopropyl) phosphate (TDBPP) and dibromoneopentyl glycol (DBNPG) are genotoxic and carcinogenic, warranting further surveillance of their ...

Genotoxicity of water extracts from hypoxis species

Toxicology in vitro, Lissabon, Portugal (2012) Keywords: Comet Assay cytome assay genotoxicity Hypoxis Abstract: There is a continuous search for new medication against many diseases. The main reason is that ...

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