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In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials
(these) activity(ies) will be explored using cell based transactivational assays also named “reporter gene assays. The MCF7 recombinant cells used here are genitically modified cells containing the firefly ...
M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.
new avenue. Here we report on the vaccine potential of two highly attenuated M.tb mutants, MGM1991 and M.tbhma::hyg (HMA), lacking all oxygenated mycolates in their cell wall. In C57BL /6 mice, stronger ...
In vitro and in vivo infectious potential of coxiella burnetii: a study on Belgian livestock isolates.
6, p.e67622 (2013) Keywords: Animals Cattle Cell Line Cell Line, Tumor Coxiella burnetii Female Genotype Goats HeLa Cells Humans Livestock mice Mice, Inbred BALB C Netherlands Q Fever Abstract: Q-fever ...
An essential role for γ-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle.
lymphoproliferative disease occurs after a prolonged asymptomatic incubation period after transmission. Our recent findings with the rabbit model indicated that AlHV-1 infection is not productive during MCF. Here, we ...
Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: implication of leucocyte recruitment
in xenograft models of human PDAC. We show here that activated NK and monocytic cells were found to be recruited by PDAC tumours upon infection with parvoviruses armed with IL-2 or the chemokine MCP-3/ ...
Autophagy and phagocytosis-like cell cannibalism exert opposing effects on cellular survival during metabolic stress4383
Publication Type: Peer reviewed scientific article Authors: J Poels; Spasic,M.R.; Gistelinck,M.; Mutert,J.; Schellens,A.; Callaerts,P.; K. Norga Source: Cell Death.Differ., Volume 19, Issue 10, ...
Cytome assay in two cell lines exposed to ELF-magnetic fields: An investigation on the relation between exposure to ELF-magnetic fields and an alleged increased risk for Alzheimer's disease.
Issue UNIVERSITY OF MALTA, La Valetta, Malta (2012) Keywords: Alzheimer C3A cytome assay ELF magnetic fields micronucleus nuclear bud SH-SY5Y Abstract: Cell division disturbances, including trisomy ...
Angiotensin IV displays only low affinity for native insulin-regulated aminopeptidase (IRAP).
Pharmacol, Volume 26, Issue 2 (2012) Keywords: Angiotensin II Animals CD13 Antigens Cell Line Chelating Agents Cho Cells Cricetinae Cricetulus Cystinyl Aminopeptidase mice Organophosphorus Compounds ...
Immunogenicity of eight Mycobacterium avium subsp. paratuberculosis specific antigens in DNA vaccinated and Map infected mice.
diagnostic tools and vaccines. Here we report on the immunogenicity of eight Map specific antigens, i.e. MAP1693 c, Ag3, MAP2677 c (identified by post-genomic and immunoproteomic analysis of Map secretome) and ...
The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer
esophageal or gastric cancer, respectively. The key molecules attracting leukocytes to local inflammatory sites are chemokines. We here provide a systematic review on the impact of CXC chemokines (binding the ...