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Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8(+) Lymphocytes in a Heterologous Challenge Model.

immune responses induced by infection. In the present study, homo- and heterologous infection experiments with two distinct T. gondii strains (IPB- LR and IPB-Gangji) were performed. The humoral and ...

Parasite distribution and associated immune response during the acute phase of Toxoplasma gondii infection in sheep.

present study, the initial phase of the infection was investigated: the parasite’s entry site, the subsequent distribution of the parasite and the host-immune response. RESULTS: Parasite DNA was already ...

Serological profiles in nursery piglets colonized with Staphylococcus aureus.

Infections Staphylococcus aureus Swine Swine Diseases Virulence Factors Abstract: At present, the immune response of pigs in relation to Staphylococcus aureus carriage is poorly understood. This study was ...

Functional characterization of in vivo effector CD4(+) and CD8(+) T cell responses in acute Toxoplasmosis: an interplay of IFN-gamma and cytolytic T cells.

protected against acute disease. In order to characterize the associated Th1 cellular immune responses in vivo, we used H2-K(k) bone marrow macrophage cell lines constitutively expressing T. gondii GRA1, GRA7 ...

An enhanced GRA1-GRA7 cocktail DNA vaccine primes anti-Toxoplasma immune responses in pigs.

whether DNA vaccination against T. gondii in pigs is able to generate immune responses known to be protective against tissue cyst formation. A GRA1- GRA7 DNA vaccine cocktail was enhanced by codon ...

GRA7 provides protective immunity in cocktail DNA vaccines against Toxoplasma gondii.

cellular immune responses was evaluated after vaccination with plasmid mixtures containing GRA1, GRA7 and ROP2. Cocktail DNA vaccinated mice developed high antibody titers against the antigens from two-gene ...

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