Search results - 6 results
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Keersmaecker; Rogiers, Vera; Tatyana Y. Doktorova Source: Archives of Toxicology (2018) Keywords: genotoxicity HepaRG In vitro screening mutagenicity qPCR array Toxicogenomics Abstract: Although the value of the ...
In vitro toxicity and genotoxic activity of aqueous leaf and fruit extracts of Ruscus hypophyllum L.
Physiologiae Plantarum, Volume 39, Issue 9 (2017) Keywords: Antigenotoxicity Comet assay Phenolic content Vitotox test Genotoxicity Ruscus hypophyllum L. Health Topics: Health and environment Santé et ...
The Vitotox and ToxTracker assays: a two-test combination for quick and reliable assessment of genotoxic hazards
reporter-based assays. In this paper we investigate the performance of two in vitro reporter-based assays, namely the Vitotox and the ToxTracker. A set of reference compounds were selected to cover not only ...
The Cytome Assay as a Tool to Investigate the Possible Association Between Exposure to Extremely Low Frequency Magnetic Fields and an Increased Risk for Alzheimer's Disease.
experimental evidence supporting this alleged association. We have performed an in vitro cytogenetic laboratory investigation to explore the plausibility of such association. Our investigation was based on ...
In silico tools and transcriptomics analyses in the mutagenicity assessment of cosmetic ingredients: a proof-of-principle on how to add weight to the evidence.
Abstract: Prior to the downstream development of chemical substances, including pharmaceuticals and cosmetics, their influence on the genetic apparatus has to be tested. Several in vitro and in vivo assays ...
Investigations of plant-derived products with the in vitro comet assay
Publication Type: Peer reviewed scientific article Authors: Luc Verschaeve Source: Frontiers in Genetics, Volume 6 (2015) Keywords: Comet Assay medicinal plants SCREENING Vitotox test Health ...