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Diagnostic accuracy of p16(INK4a) immunohistochemistry in oropharyngeal squamous cell carcinomas: A systematic review and meta-analysis.
mRNA detection using an amplification-based method (gold standard to indicate a transforming relevance of HPV) in OPSCC. Testing with one or more comparator tests (HPV DNA PCR, HPV DNA in situ ...
Which high-risk HPV assays fulfil criteria for use in primary cervical cancer screening?
(matrix-assisted laser desorption-ionization time-of-flight). The APTIMA HPV assay targeting E6 / E7 mRNA of hrHPV was also fully validated. However, the cross-sectional equivalency criteria of the 2009 guidelines ...
HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis.
carcinogenesis (E6 / E7 mRNA and p16(INK4 a)). If it was not possible to abstract the required information directly from the paper, we contacted the authors. We did a meta-analysis to produce pooled prevalence ...
HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis
/ E7 mRNA and p16INK4a). If it was not possible to abstract the required information directly from the paper, we contacted the authors. We did a meta-analysis to produce pooled prevalence estimates ...
Evidence regarding human papillomavirus testing in secondary prevention of cervical cancer.
(higher sensitivity, similar specificity) than repeat cytology to triage women with equivocal Pap smear results. Several other tests show at least similar accuracy but mRNA testing with the APTIMA (®) ...
Chapter 10: HPV testing on cervical cancer specimens: which assay can be used in cervical cancer screening.
hrHPV mRNA tests with validated DNA tests. These reviews are updated and summarised in this chapter. The assays that can be considered as clinically validated are listed in Text Box 1: Standard comparator ...