Search results - 26 results
Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism31064
mycobacteria-containing vacuole in resting macrophages but not in the more acidic phagolysosomal compartment of activated macrophages. However, the urease-mediated alkalizing effect did not confer any growth advantage to ...
Straightforward palladium-mediated synthesis and biological evaluation of benzo[j]phenanthridine-7,12-diones as anti-tuberculosis agents
Kimpe Source: Eur.J.Med.Chem., Volume 48, Number 68, p.57- 68 (2012) Keywords: Activity Agent Agents Antimicrobial article AS bacteria Belgium Development disease Diseases DRUG Drug Resistance drugs ...
Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors31058
Design DRUG Drug Design drug effects Drug Synergism electronic Ethionamide EVALUATION exposure expression France Human im IS journal Macrophages metabolism mice microbiology Microsomes,Liver ...
Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection36574
interactions IS journal Kinetics Lung lymphocyte Lymphocytes Macrophage Macrophages MODEL models Mycobacterium Mycobacterium tuberculosis need observed ON pathology Pharmacokinetic prevention & control rats ...
Haemorrhagic diathesis in neonatal calves: an emerging syndrome in Europe.
lymphoid tissue was the most prominent finding on histology. Activated macrophages and haemophagocytosis were seen on bone marrow cytology from two live calves. Polymerase chain reaction for bovine viral ...
Kinetic and biologic properties of recombinant ChIFN-gamma expressed via CELO-virus vector.
produced via the baculovirus expression system (Bac-ChIFN-gamma). CELO-ChIFN-gamma inhibited the replication of cytolytic virus in chicken embryo fibroblasts (CEF s) and activated macrophages in a better ...
The effect of vaccination with a Salmonella enteritidis aroA mutant on early cellular responses in caecal lamina propria of newly-hatched chickens.
Bacterial Granulocytes Immunoglobulin A Macrophages Mutation Salmonella enteritidis Salmonella Infections Salmonella Vaccines T-Lymphocytes Abstract: When newly hatched chicks are inoculated with a Salmonella ...
Turkey and chicken interferon-gamma, which share high sequence identity, are biologically cross-reactive.
(2001) Keywords: Animals Cells, Cultured Chickens COS Cells Cross Reactions Enzyme-Linked Immunosorbent Assay Flow Cytometry Interferon-gamma Macrophages Recombinant Proteins Sequence Homology, Amino Acid ...
Effect of TNF-alpha on LH and IGF-I modulated chicken granulosa cell proliferation and progesterone production during follicular development.
IGF-I and its interaction with LH. Conditioned medium of LPS-activated HD11 macrophages mimicked the effects of TNF-alpha and its interaction with IGF-I and LH on progesterone production and cell ...
Comparison of biological activities of natural and recombinant chicken interferon-gamma.
replication of cytolytic viruses in chicken embryo fibroblasts and to activate macrophages, as was determined by nitric oxide production. Levels ranging between 100 and 300 microg/ml of BacChIFN-gamma could be ...