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Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

using the approach called RNA tag-Seq, multiple samples were combined in one run, reducing time and cost.   Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

multiple samples were combined in one run, reducing time and cost.   Material/methods: For each drug (isoniazid, rifampicin, ethambutol, capreomycin, amikacin, linezolid, moxifloxacin and bedaquilin), twice ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

of resistance. Materials &  Methods First, the global transcriptional response of two TB strains to 10 anti- TB drugs was determined using RNA taq-Seq. A set of highly responsive genes was selected for each ...

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