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Risk assessment of ochratoxin A in food
characterisation of neoplastic effects, a BMDL10 of 14.5 μg/kg bw per day was calculated from kidney tumours seen in rats. The estimation of chronic dietary exposure resulted in mean and 95th percentile levels ...
Risk assessment of chlorinated paraffins in feed and food
as the target organ. The Panel selected as reference points a BMDL10 of 2.3 mg/kg bw per day for increased incidence of nephritis in male rats, and of 36 mg/kg bw per day for increased relative kidney ...
Comments on the “Evaluation of the Genotoxicity of Cell Phone Radiofrequency Radiation in Male and Female Rats and Mice Following Subchronic Exposure” by Smith‐Roe et al.
female rats and mice following subchronic exposure. Smith-Roe SL, Wyde ME, Stout MD, Winters JW, Hobbs CA, Shepard KG, Green AS, Kissling GE, Shockley KR, Tice RR, Bucher JR, Witt KL.Environ Mol Mutagen. ...
Risk assessment of aflatoxins in food
0.4 lg/kg body weight (bw) per day for the incidence of HCC in male rats following AFB1 exposure to be used in a margin of exposure (MOE) approach. The calculation of a BMDL from the human data was not ...
In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin
Mutagenic potential was assessed by the Ames test using Salmonella typhimurium strains TA98 and TA100. Oral acute toxicity was carried out by administration of a single dose of 2000 mg/kg b.w. to Wistar rats ...
In vitro antigenotoxic activity, in silico ADME prediction and protective effects against aflatoxin B1 induced hepatotoxicity in rats of an Erythrina latissima stem bark extract
rats induced by the same agent. Male Wistar rats were orally treated with ELBE (20 mg/kg, 50 mg/kg and 100 mg/kg) or curcumin (500 mg/kg) combined with piperine (20 mg/kg) — positive control, for 8 days ...
Short-term biodistribution and clearance of intravenously administered silica nanoparticles
examined the biodistribution and excretion in female Sprague-Dawley rats of NM-200, a well characterized nanostructured silica representative for food applications. A single intravenous injection of NM-200 ...
Human absorption of silver ENM: through particles or ions?
orally administered silver ENM with the tissue distribution pattern of silver ENM and a silver salt that were administered by intravenous (IV) injection. Female rats were exposed to a single dose of ...
Genotoxicity and genomic instability caused by intermediate frequency magnetic fields in rat astrocytes
Publication Type: Dissertation Authors: Blomme, Amélie Source: UAntwerpen and University of Eastern Finland, Antwerp, Belgium- Kuopio, Finland, p.NA (2017) Accession Number: NA Keywords: astrocytes Comet Assay cytotoxicity Genomic Instability genotoxicity ...
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.
C-epsilon rats Rats, Sprague-Dawley Receptor, Metabotropic Glutamate 5 Transduction, Genetic Abstract: A critical role has been assigned to protein kinase C (PKC)ε in the control of intracellular calcium ...