Search results - 71 results
Advancing regulatory dialogue: In silico models for improved vaccine biomanufacturing- an expert meeting report.
relevant to vaccine biomanufacturing and shelf life. The stability model was highlighted as having the most significant impact on the common technical document (CTD) due to its potential to streamline data ...
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
identified following screening against the most relevant trypanosome species. Selected hit compounds were extensively tested for metabolic stability, potency in mouse models for the various species, ...
Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial pathogens.
isolates into the same analysis produced stable and highly accurate phylogenomic results. The resulting phylogenies for these two outbreaks stabilized after ~20 hours of sequencing for ONT R9 and ~8 hours ...
Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial pathogens.
isolates into the same analysis produced stable and highly accurate phylogenomic results. The resulting phylogenies for these two outbreaks stabilized after ~20 hours of sequencing for ONT R9 and ~8 hours ...
Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial pathogens.
isolates into the same analysis produced stable and highly accurate phylogenomic results. The resulting phylogenies for these two outbreaks stabilized after ~20 hours of sequencing for ONT R9 and ~8 hours ...
Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial pathogens.
outbreaks stabilized after ~20 hours of sequencing for ONT R9 and ~8 hours for ONT R10. This study provides a proof of concept for using ONT R10, either in isolation or in combination with Illumina, for rapid ...
Development of a monoclonal antibody sandwich ELISA for the determination of antigen content and quality in diphtheria vaccines.
testing and may be suitable to serve as the stability indicating test in replacement of the current in vivo potency test. Service: Qualité des vaccins et produits sanguins Kwaliteit van vaccins en ...
Characterization of a Bacteriophage GEC_vB_Bfr_UZM3 Active against.
represent a strictly lytic phage belonging to a siphovirus morphotype. It is characterized by high stability at body temperature and in pH environments for about 6 h. Whole genome sequencing analysis of the ...
Ultrastable Silver Nanoparticles for Rapid Serology Detection of Anti-SARS-CoV-2 Immunoglobulins G.
Sensitivity and Specificity Silver Spike Glycoprotein, Coronavirus Abstract: Dipstick assays using silver nanoparticles (AgNPs) stabilized by a thin calix [4]arene-based coating were developed and used for the ...
Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines.
disease. However, the usefulness of a vaccine is determined by a multiplicity of factors which include stability, efficiency, safety and ease of use, to name a few. Although the vaccination campaign in the ...